QUICK ANSWER
- Epimedium's main compound, icariin, is studied on the nitric oxide pathway.
- Lab work calls it a weak PDE5 inhibitor, far weaker than prescription drugs.
- Human data are limited; it may interact with blood thinners and blood pressure medicine.
What Epimedium is
Epimedium, also called horny goat weed, has been used in traditional Chinese medicine for centuries for male vitality.
What icariin does in the lab
A 2010 study described icariin as a weak PDE5 inhibitor with effects on nitric oxide signaling (J Sex Med), orders of magnitude weaker than prescription drugs.
What is known in humans
Controlled human trials are limited, so claims should stay modest.
Interactions
MedlinePlus lists possible interactions with blood thinners and blood pressure medicine (MedlinePlus). See the full safety guide.
Epimedium in ErecPower
It anchors the circulation route of the formula. Compare it with the other eight in ingredients graded by evidence.
Frequently asked questions
Is horny goat weed like Viagra?
No. Icariin is a far weaker PDE5 inhibitor in lab studies, and human evidence is limited.
Who should avoid Epimedium?
People on blood thinners or blood pressure medicine should talk to a doctor first.
This article is general information, not medical advice. Talk to your doctor or pharmacist before starting any supplement. We may earn a commission from links on this page; see our disclosure and editorial standards.


